Identifying novel genetic variants for brain amyloid deposition: a genome-wide association study in the Korean population.

Hang-Rai KimSang-Hyuk JungJaeho KimHyemin JangSung Hoon KangSong HwangboJun Pyo KimSo Yeon KimBeomsu KimSoyeon KimJee Hyang JeongSoo Jin YoonKyung Won ParkEun-Joo KimBora YoonJae-Won JangJin Yong HongSeong Hye ChoiYoung NohKo Woon KimSi Eun KimJin San LeeNa-Yeon JungJuyoun LeeByeong C KimSang Joon SonChang Hyung HongDuk L NaSang Won SeoHong-Hee WonHee Jin Kim

Published in: Alzheimer's research & therapy (2021)

The novel genetic variants associated with FGL2 decreased risk of Aβ positivity in the Korean population. This finding may provide a candidate therapeutic target for AD, highlighting the importance of genetic studies in diverse populations.

Keyphrases

genome wide association study
resting state
white matter
multiple sclerosis
functional connectivity
copy number
dna methylation
case control
subarachnoid hemorrhage