Acute and Chronic Kidney Disease Worsen Outcomes in Experimental Sepsis.
Deana F FloydJames F ColbertFrances FengSeth B FurgesonJohn R MontfordPublished in: Kidney360 (2024)
These data confirm that acute bacterial infection can be modeled in animals with established kidney disease; and suggest that the clinical state of kidney disease (AKD versus CKD) may influence host susceptibility to infection more than the degree of kidney failure alone.