Circ_0008146 Exacerbates Ferroptosis via Regulating the miR-342-5p/ACSL4 Axis After Cerebral Ischemic/Reperfusion.
Cai-Dong LiuQiang PengShi-Yao WangYang DengZhong-Yuan LiZhao-Han XuLiang WuYing-Dong ZhangRui DuanPublished in: Journal of inflammation research (2024)
This study provides the first in vivo evidence to show that circ_0008146 exacerbates neuronal ferroptosis after AIS via the miR-342-5p/ACSL4 axis. Furthermore, miR-342-5p/ACSL4 axis holds promise as a viable therapeutic target and practical biomarkers for AIS patients.