Thyroid Function Tests in Children and Adolescents with Trisomy 21: Definition of Syndrome-Specific Reference Ranges.
Alessandro CattoniSilvia MolinariGiulia CapitoliNicoletta MaseraMaria Laura NicolosiSilvia BarzaghiGiulia MarzialiAlessandra LazzerottiAlessandra GazzarriChiara VimercatiDebora SalaAndrea BiondiStefania GalimbertiChiara FossatiPublished in: The Journal of clinical endocrinology and metabolism (2023)
By longitudinally assessing TFT in a wide pediatric DS population, we outlined the syndrome-specific reference nomograms for TSH, FT3 and FT4 and demonstrated a persistent upward shift of TSH compared to non-syndromic children.