Targeted metabolomic profiling of low and high grade serous epithelial ovarian cancer tissues: a pilot study.

Gunjal GargRay Oliver Bahado-SinghPraveen KumarOnur TurkogluDavid G MutchMatthew A PowellBarry RosenRay O Bahado-SinghStewart F Graham

Published in: Metabolomics : Official journal of the Metabolomic Society (2018)

These previously unreported biochemical changes provide a framework for future metabolomic studies for the development of EOC biomarkers. Finally, pharmacologic targeting of the key metabolic pathways identified herein could lead to novel and effective treatments of EOC.

Keyphrases

high grade
low grade
cancer therapy
gene expression
single cell
drug delivery
case control