Mechanistic explorations on the decarboxylative allylation of amino esters via dual photoredox and palladium catalysis.
Qingqing ChenRuizhong ZhangYanfeng DangPublished in: Organic & biomolecular chemistry (2023)
Mechanistic studies reveal that the decarboxylative allylation of amino esters via dual photoredox and palladium catalysis occurs via oxidation giving π-allyl-Pd(II) species and carboxylate, which is oxidized by *Ir(III)-catalyst offering benzyl radicals. The alkylated product is formed via an S N 2 pathway. Single-electron transfer between Pd(I)-species and Ir(II)-catalysis restores both catalysts.