Dispersive micro-solid phase extraction based on two MOFs as highly effective adsorbents for analysis of nilotinib in plasma and wastewater.
Azra TakhvarSomaye AkbariEffat SouriReza AhmadkhanihaAli MorsaliMohammad Reza KhoshayandMohsen AminiAlireza TaheriPublished in: Daru : journal of Faculty of Pharmacy, Tehran University of Medical Sciences (2024)
HPLC-UV determination of nilotinib after the D-µ-SPE method showed acceptable accuracy and precision in both plasma and wastewater. In comparison between the two adsorbents, the extraction procedure was easier and faster with MIL-53(Al) as the adsorbent.
Keyphrases
- solid phase extraction
- high performance liquid chromatography
- molecularly imprinted
- liquid chromatography tandem mass spectrometry
- simultaneous determination
- gas chromatography mass spectrometry
- tandem mass spectrometry
- liquid chromatography
- chronic myeloid leukemia
- wastewater treatment
- ultra high performance liquid chromatography
- gas chromatography
- anaerobic digestion
- minimally invasive
- mass spectrometry
- aqueous solution