Mast cells mediate early neutrophil recruitment and exhibit anti-inflammatory properties via the formyl peptide receptor 2/lipoxin A4 receptor.
Ellen L HughesFelix BeckerRoderick J FlowerJulia C BuckinghamFelicity N E GavinsPublished in: British journal of pharmacology (2017)
Data presented here provide evidence for a role of MCs, which are ideally positioned in close proximity to the vasculature, to act as sentinel cells in neutrophil extravasation and resolution of inflammation via the AnxA1-FPR2/ALX pathway.