Serum testosterone levels and testosterone supplementation in cirrhosis: A systematic review.

Nanfu DengNiharika MallepallyFrederick B PengAleem KanjiMarco MarcelliFasiha Kanwal

Published in: Liver international : official journal of the International Association for the Study of the Liver (2021)

Low serum testosterone is associated with increased morbidity and mortality in cirrhosis patients. Testosterone supplementation improved intermediate endpoints, but there was no conclusive data on clinical outcomes. Testosterone supplementation may be a promising strategy to improve frailty and decrease significant clinical complications in cirrhosis.

Keyphrases

replacement therapy
end stage renal disease
chronic kidney disease
prognostic factors
peritoneal dialysis
big data
patient reported outcomes
deep learning
community dwelling