Liberal or Restrictive Transfusion Strategy in Patients with Traumatic Brain Injury.
Alexis Fournier TurgeonDean A FergussonLucy ClaytonMarie-Pier PattonXavier NeveuTimothy S WalshAnnemarie DochertyLuiz M MalbouissonSébastien Pili-FlouryShane W EnglishRyan ZarychanskiLynne MoorePaule Lessard BonaventureVincent LarocheMichael VerretDamon C ScalesNeill K J AdhikariJonathan GreenbaumAndreas KramerVanesa Garnelo ReyIan Michael BallKosar KhwajaMatt WiseDaniel HarveyFrançois LamontagneRussell ChabanneAlmunder AlgirdStephan KrueperJulien PottecherFrederick ZeilerJonathan RhodesAndrea RigamontiKaren E A BurnsJohn MarshallDonald E GriesdaleLaís Silva SisconettoDemetrios J KutsogiannisClaire RogerRobert GreenJ Gordon BoydJudith WrightEmmanuel CharbonneyPriya NairTimothy AstlesEric SyPaul C HébertMichael ChasséAlwyn GomezTim RamsayMonica TaljaardAlison Fox-RobichaudAlan TinmouthMaude St-OngeOlivier CosterousseFrançois Lauziernull nullPublished in: The New England journal of medicine (2024)
In critically ill patients with traumatic brain injury and anemia, a liberal transfusion strategy did not reduce the risk of an unfavorable neurologic outcome at 6 months. (Funded by the Canadian Institutes of Health Research and others; HEMOTION ClinicalTrials.gov number, NCT03260478.).