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Accessing local electron-beam induced temperature changes during in situ liquid-phase transmission electron microscopy.

Birk FritschAndreas HutzlerMingjian WuSaba KhadivianazarLilian VoglMichael P M JankMartin MärzErdmann Spiecker
Published in: Nanoscale advances (2021)
A significant electron-beam induced heating effect is demonstrated for liquid-phase transmission electron microscopy at low electron flux densities using Au nanoparticles as local nanothermometers. The obtained results are in agreement with theoretical considerations. Furthermore, the impact of beam-induced heating on radiolysis chemistry is estimated and the consequences of the effect are discussed.
Keyphrases
  • electron microscopy
  • high glucose
  • diabetic rats
  • endothelial cells
  • oxidative stress
  • sensitive detection