Repeat MRI during active surveillance: natural history of prostatic lesions and upgrading rates.
Stefano LuzzagoMattia Luca PiccinelliFrancesco A MistrettaRoberto BianchiGabriele CozziEttore Di TrapaniAntonio CioffiMichele CatellaniMatteo FontanaLetizia Maria Ippolita JannelloFrancesco Maria Gerardo BotticelliGiulia MarvasoSarah AlessiPaola PricoloMatteo FerroDeliu-Victor MateiBarbara A Jereczek-FossaNicola FuscoGiuseppe PetraliaOttavio de CobelliGennaro MusiPublished in: BJU international (2021)
During AS, approximately 27% of patients experience mpMRI progression at first repeat MRI. However, the rates of mpMRI progression decrease over time at subsequent mpMRI scans. Patients with stable mpMRI findings and with PSAD < 0.15 ng/mL/mL could safely skip surveillance biopsies. Conversely, patients who experience mpMRI progression should undergo a prostate biopsy.