Hearing dysfunction heralds an increase in non-motor burden and a worse quality of life in Parkinson's disease: new insights from non-motor spectrum.

Elena GarastoAlessandro StefaniMariangela PierantozziMatteo ContiArturo MoletiRenata SistoAndrea VizianoClaudio LiguoriTommaso SchirinziNicola Biagio MercuriRocco Cerroni

Published in: Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology (2024)

This study demonstrated that PD patients with HI have a greater burden of NMS and lower related QoL and functioning. Our results highlight the importance to reconsider HI as a NMS, in parallel with the others. HI evaluation, even in asymptomatic patients, may reveal a wider pathology with a worse QoL.

Keyphrases

end stage renal disease
ejection fraction
newly diagnosed
chronic kidney disease
oxidative stress
peritoneal dialysis
genome wide
single cell
hearing loss
clinical evaluation