C18-COOH Silica: Preparation, Characterisation and Its Application in Purification of Quaternary Ammonium Alkaloids from Coptis chinensis.
Qing WangYao LongLin YaoMao YeLi XuPublished in: Phytochemical analysis : PCA (2017)
A multi-functionalised silica was synthesised via "click chemistry". As the high-performance liquid chromatographic stationary phase, the C18-COOH silica could be operated in trimodal reversed-phase/weak cation exchange/hydrophilic interaction mode. The C18-COOH silica also exhibited potential as solid-phase extraction sorbent in the purification of quaternary ammonium alkaloids from complex matrices. Copyright © 2017 John Wiley & Sons, Ltd.
Keyphrases
- solid phase extraction
- molecularly imprinted
- liquid chromatography
- ionic liquid
- simultaneous determination
- high performance liquid chromatography
- liquid chromatography tandem mass spectrometry
- tandem mass spectrometry
- gas chromatography mass spectrometry
- mass spectrometry
- ultra high performance liquid chromatography
- high resolution
- risk assessment