Cardiac failure in patients treated with azacitidine, a pyrimidine analogue: Case reports and disproportionality analyses in Vigibase.
Justine PerinoNathan MottalYohann BohbotVincent ServantAude BerroneauPierre PoustisPierre FenauxKamel LaribiAude CharbonnierEmilien BilionClaire CalmettesBernard BégaudArnaud PigneuxNoël MilpiedGhada Miremont-SalaméHélène ThéophileSophie Dimicoli-SalazarPublished in: British journal of clinical pharmacology (2020)
This study points to the potential role of AZA in the occurrence of CF. Cardiac evaluation before AZA initiation and regular monitoring of cardiac function during AZA treatment should be performed in patients with a history of cardiovascular disease.