Antisense therapy in a rat model of Alexander disease reverses GFAP pathology, white matter deficits, and motor impairment.
Tracy L HagemannBerit PowersNi-Hsuan LinAhmed F MohamedKaterina L DagueSeth C HannahGemma BachmannCurt MazurFrank RigoAbby L OlsenMel B FeanyMing-Der PerngRobert F BermanAlbee MessingPublished in: Science translational medicine (2021)
[Figure: see text].