Gene Expression Profiling of Subcutaneous Adipose Tissue Reveals New Biomarkers in Acromegaly.

Camilla M Falch Mai Christiansen Arlien-SøborgJakob DalArvind Y M SundaramAnnika E MichelsenThor UelandLinn Guro OlsenAnsgar HeckJens BollerslevJens Otto L JørgensenNicoleta C Olarescu

Published in: European journal of endocrinology (2023)

AT in active acromegaly is associated with a gene expression profile of fibrosis and inflammation, which may corroborate the hyper-metabolic state and provide a means for identifying novel biomarkers.

Keyphrases

gene expression
adipose tissue
oxidative stress
dna methylation
insulin resistance
genome wide
growth hormone
high fat diet
copy number
single cell
skeletal muscle