Lifespan Neurodegeneration Of The Human Brain In Multiple Sclerosis.
Pierrick CoupéVincent PlancheBoris MansencalReda A KamrouiIsmail KoubiyrJosé V ManjonThomas TourdiasPublished in: bioRxiv : the preprint server for biology (2023)
Subcortical atrophy was more pronounced than cortical atrophy. The thalamus was the most impacted structure with a very early divergence in life. It paves the way toward utilization of these lifespan models for future preclinical/prodromal prognosis and monitoring of MS.