Whole-genome single nucleotide polymorphism-based linkage analysis in spondyloarthritis multiplex families reveals a new susceptibility locus in 13q13.
Félicie CostantinoEmmanuel ChaplaisTifenn LeturcqRoula Said-NahalAriane LeboimeElena ZinovievaDiana ZelenikaIvo GutCéline CharonGilles ChiocchiaMaxime BrebanHenri-Jean GarchonPublished in: Annals of the rheumatic diseases (2015)
We report here for the first time a significant linkage between 13q13 and SpA. Identification of susceptibility factor inside this chromosomal region through targeted sequencing in linked families is underway.