A 10-year experience in testicular tissue cryopreservation for boys under 18 years of age: What can be learned from 350 cases?

This large series of pediatric FP shows that this procedure is well accepted, feasible, and safe in the short term, strengthening its place in the clinical care pathway of young patients requiring a highly gonadotoxic treatment. Our results demonstrate that CTT post-chemotherapy does not impair the chance to preserve spermatogonia in the testicular tissue except when the treatment includes alkylating agents. More data on post-CTT follow-up are still required to ensure the long-term safety and usefulness of the procedure. This article is protected by copyright. All rights reserved.