Reiterative infusions of MSCs improve pediatric osteogenesis imperfecta eliciting a pro-osteogenic paracrine response: TERCELOI clinical trial.
Arantza InfanteBlanca GenerMiguel VázquezNerea OlivaresArantza ArrietaGema GrauIsabel LlanoLuis MaderoAna Maria BuenoBelén SagastizabalDaniela GerovskaMarcos Jesus Araúzo-BravoItziar AstigarragaClara I RodríguezPublished in: Clinical and translational medicine (2021)
Our results demonstrate the feasibility and potential of reiterative MSCs infusion for two pediatric OI and highlight the paracrine response shown by patients as a consequence of MSCs treatment.