Reiterative infusions of MSCs improve pediatric osteogenesis imperfecta eliciting a pro-osteogenic paracrine response: TERCELOI clinical trial.

Arantza Infante Blanca GenerMiguel VázquezNerea OlivaresArantza ArrietaGema GrauIsabel Llano Luis MaderoAna Maria BuenoBelén SagastizabalDaniela Gerovska Marcos Jesus Araúzo-BravoItziar AstigarragaClara I Rodríguez

Published in: Clinical and translational medicine (2021)

Our results demonstrate the feasibility and potential of reiterative MSCs infusion for two pediatric OI and highlight the paracrine response shown by patients as a consequence of MSCs treatment.

Keyphrases

mesenchymal stem cells
clinical trial
umbilical cord
end stage renal disease
newly diagnosed
ejection fraction
bone marrow
low dose
open label
phase ii
anti inflammatory
patient reported outcomes
climate change
patient reported
double blind
smoking cessation
human health
bone regeneration