CXCR4 peptide-based fluorescence endoscopy in a mouse model of Barrett's esophagus.

Sabrina MarcazzanMarcos J Braz CarvalhoMatthias KonradJulia StrangmannAnna TenditnayaTheresa BaumeisterRoland M SchmidHans-Jürgen WesterVasilis NtziachristosDimitris GorpasTimothy C WangMargret SchotteliusMichael Quante

Published in: EJNMMI research (2022)

This preliminary preclinical study shows that CXCR4-targeted fluorescence endoscopy using MK007 can detect dysplastic lesions in a mouse model of Barrett's esophagus. Further investigations are needed to assess its use in the clinical setting.

Keyphrases

mouse model
single molecule
small bowel
energy transfer
cell migration
stem cells
cell therapy
mesenchymal stem cells
quantum dots