Dynamics of Thrombogenicity and Platelet Function and Correlation with Bleeding Risk in Patients Undergoing M-TEER Using the PASCAL System.
Miriam EuperJürgen SchreieckMareike BladtMonika ZdanyteAndreas GoldschmiedManuel SigleDominick J AngiolilloDiana Adrienne GorogMia Ravn JacobsenRikke SørensenDominik RathMeinrad GawazTobias GeislerPublished in: Thrombosis and haemostasis (2024)
This study indicates that thrombogenicity might be affected immediately after M-TEER probably due to changes in flow conditions. In particular, platelet aggregation involving the ADP receptor pathway significantly correlated with postprocedural bleeding events. Whether these results could guide peri-interventional antithrombotic therapy and improve peri- and postprocedural outcome requires further investigation.