Circulating tumor DNA for monitoring colorectal cancer: A prospective observational study to assess the presence of methylated SEPT9 and VIM promoter genes and its role as a biomarker in colorectal cancer management.

Puviarasan Gopal Zeeshan Ahmed Ravikanth Venkata Vishnubhotla Guduru Venkat Rao Pradeep Rebala

Published in: Turkish journal of surgery (2023)

In our study, only 6.66% CRC patients showed hypermethylation and there was no association of methylation patterns in the both genes (complete, partial, and no methylation) with any of the parameters like age, sex, TNM stage, CEA, and histology.

Keyphrases

circulating tumor
genome wide
dna methylation
end stage renal disease
cell free
circulating tumor cells
ejection fraction
chronic kidney disease
newly diagnosed
gene expression
prognostic factors
transcription factor
single molecule
patient reported