Comparison of [68Ga]-FAPI PET/CT and [18F]-FDG PET/CT in Multiple Myeloma: Clinical Experience.

Umut ElbogaErtan SahinYusuf Burak CayirliMerve OkuyanGokmen AktasHandan Haydaroglu SahinIlkay DoganTulay KusDervis Murat AkkurdUfuk CimenVuslat MumcuBenan KilbasYusuf Zeki Celen

Published in: Tomography (Ann Arbor, Mich.) (2022)

No significant superiority was observed in [68Ga]FAPI PET/CT over [18F]FDG PET/CT in patients with MM. However, [68Ga]FAPI PET/CT can be utilized as a complementary imaging method to [18F]FDG PET/CT in some settings, especially in low-[18F]FDG affinity and inconclusive cases. Considering the favorable aspects of [68Ga]FAPI PET/CT in MM, such as low background activity, absence of non-specific bone marrow, and physiological brain involvement, further studies with a larger sample size should be conducted.

Keyphrases

pet ct
bone marrow
positron emission tomography
multiple myeloma
mesenchymal stem cells
multiple sclerosis
mass spectrometry
brain injury
subarachnoid hemorrhage