Higher levels of SARS-CoV-2 genetic variation in immunocompromised patients: a retrospective case-control study.

Romane GuilbaudAnna-Maria Franco YustiValentin LeducqKaren ZafilazaAntoine Bridier-NahmiasEve TodescoCathia SoulieAntoine FauchoisQuentin Le HingratLaura KramerTiphaine GoulenokMathilde SalpinEric DaugasRichard DorentSébastien OttavianiGérard ZalcmanJade GhosnSylvain ChoquetPatrice CacoubZahir AmouraBenoit BarrouxValérie PourcherJean-Philippe SpanoMartine LouetAnne-Geneviève MarcelinVincent CalvezCharlotte CharpentierDiane DescampsStéphane MarotValentine Marie FerréRomain Coppée

Published in: The Journal of infectious diseases (2023)

This study found that SARS-CoV-2 infection in immunocompromised patients is associated with higher genetic diversity, which could lead to the emergence of new SARS-CoV-2 variants with possible immune evasion or different virulence characteristics.

Keyphrases

sars cov
end stage renal disease
newly diagnosed
ejection fraction
peritoneal dialysis
prognostic factors
escherichia coli
dna methylation
cystic fibrosis
patient reported