Genomic, Transcriptomic, and Proteomic Depiction of Induced Pluripotent Stem Cells-Derived Smooth Muscle Cells As Emerging Cellular Models for Arterial Diseases.

Lu LiuCharlène Jouve Josephine Henry Takiy-Eddine Berrandou Jean-Sébastien HulotAdrien GeorgesNabila Bouatia-Naji

Published in: Hypertension (Dallas, Tex. : 1979) (2023)

Both induced pluripotent stem cell-derived SMCs models present complementary cellular phenotypes of high relevance to SMC plasticity. These cellular models present high potential to study functional regulation at genetic risk loci of main arterial diseases.

Keyphrases

induced pluripotent stem cells
genome wide
high glucose
gene expression
dna methylation
diabetic rats
climate change
risk assessment
human health