Cannabinoid receptor 2-63 RR variant is independently associated with severe necroinflammation in HIV/HCV coinfected patients.
Caterina SagnelliCaterina Uberti-FoppaHamid HassonGiulia BelliniCarmine MinichiniStefania SalpietroEmanuela MessinaDiletta BarbanottiMarco MerliFrancesca PunzoNicola CoppolaAdriano LazzarinEvangelista SagnelliFrancesca RossiPublished in: PloS one (2017)
This study shows interesting interplay between the CB2-RR variant and liver necroinflammation in chronic hepatitis patients with HIV/HCV coinfection, an observation of clinical value that coincides with the interest in the use of the CB2 agonists and antagonists in clinical practice emerging from the literature.
Keyphrases
- hepatitis c virus
- human immunodeficiency virus
- antiretroviral therapy
- hiv positive
- hiv infected
- hiv testing
- end stage renal disease
- clinical practice
- hiv aids
- ejection fraction
- newly diagnosed
- men who have sex with men
- chronic kidney disease
- systematic review
- peritoneal dialysis
- prognostic factors
- early onset
- patient reported outcomes
- south africa
- binding protein