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Re-evaluation of cefepime or piperacillin-tazobactam to decrease use of carbapenems in extended-spectrum beta-lactamase-producing Enterobacterales bloodstream infections (REDUCE-BSI).

Catherine H VuVeena VenugopalanBarbara A SantevecchiStacy A VoilsReuben RamphalKartikeya CherabuddiKathryn DeSear
Published in: Antimicrobial stewardship & healthcare epidemiology : ASHE (2022)
Compared to CBPs, FEP and PTZ did not result in greater mortality or decreased clinical efficacy for the treatment of ESBL-E BSI caused by susceptible organisms.
Keyphrases
  • escherichia coli
  • gram negative
  • cardiovascular events
  • type diabetes
  • combination therapy
  • coronary artery disease
  • replacement therapy