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Intra-patient variability of iodine quantification across different dual-energy CT platforms: assessment of normalization techniques.

Simon LennartzJinjin CaoNisanard PisuchpenShravya Srinivas-RaoJoseph J LocascioAnushri ParakhPeter F HahnAchille MiletoDushyant SahaniAvinash R Kambadakone
Published in: European radiology (2024)
• Iodine concentration showed the least variability between scanner types in the kidneys (range 10.92-15.76%) and highest variability in the liver (range 22.85-29.08%). • Normalizing tissue-specific iodine concentrations against the overall iodine load yielded the greatest reduction of variability between scanner types for 2/3 inter-scanner comparisons in the liver and for all (3/3) inter-scanner comparisons in the kidneys and pancreas, respectively. • However, even after normalization, the dual-energy CT scanner type was found to be the factor significantly influencing variability of iodine concentration in the liver and pancreas.
Keyphrases
  • dual energy
  • image quality
  • computed tomography
  • contrast enhanced
  • positron emission tomography
  • magnetic resonance
  • case report