Easy Access to Phenanthridinones via Metal-Free Cascade Benzannulation and C-N Bond Formation.
null PreetiKailas V KallurkarPrathama S MainkarRaju AdepuSrivari ChandrasekharPublished in: Organic letters (2023)
A concise route for the synthesis of dihydrobenzo[ j ]phenanthridinones has been disclosed through an aryne annulation strategy under metal-free reaction conditions. The reaction involves multiple C-C and C-N bond cleavages/formations via Diels-Alder reaction, aromatization-driven C-N bond cleavage, and amide formation.