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Easy Access to Phenanthridinones via Metal-Free Cascade Benzannulation and C-N Bond Formation.

null PreetiKailas V KallurkarPrathama S MainkarRaju AdepuSrivari Chandrasekhar
Published in: Organic letters (2023)
A concise route for the synthesis of dihydrobenzo[ j ]phenanthridinones has been disclosed through an aryne annulation strategy under metal-free reaction conditions. The reaction involves multiple C-C and C-N bond cleavages/formations via Diels-Alder reaction, aromatization-driven C-N bond cleavage, and amide formation.
Keyphrases
  • electron transfer
  • transition metal
  • dna binding
  • transcription factor