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Initial dose recommendation for sirolimus in paediatric kaposiform haemangioendothelioma patients based on population pharmacokinetics and pharmacogenomics.

Xiao ChenDong-Dong WangHong XuZhi-Ping Li
Published in: The Journal of international medical research (2021)
The recommendation for the initial sirolimus dose in paediatric kaposiform haemangioendothelioma patients was based on population pharmacokinetics and pharmacogenomics. This study may provide practical value for sirolimus clinical use in paediatric kaposiform haemangioendothelioma patients.
Keyphrases
  • end stage renal disease
  • newly diagnosed
  • ejection fraction
  • chronic kidney disease
  • emergency department
  • intensive care unit
  • prognostic factors
  • peritoneal dialysis
  • clinical decision support