Cryptococcal antigen positivity combined with the percentage of HIV-seropositive samples with CD4 counts <100 cells/μl identifies districts in South Africa with advanced burden of disease.
Lindi-Marie CoetzeeNaseem CassimCharlotte SriruttanMabatho MhlangaNelesh P GovenderDeborah Kim GlencrossPublished in: PloS one (2018)
Existing CD4 testing services were used to rapidly scale up CrAg reflex testing in South Africa. Districts with advanced HIV and CrAg disease burden were identified that need further investigation of patient management interventions.
Keyphrases
- hiv positive
- south africa
- antiretroviral therapy
- men who have sex with men
- hiv testing
- hiv infected
- human immunodeficiency virus
- induced apoptosis
- hiv aids
- hepatitis c virus
- healthcare
- cell cycle arrest
- primary care
- physical activity
- mental health
- nk cells
- case report
- risk factors
- gene expression
- cell death
- endoplasmic reticulum stress
- signaling pathway
- cell proliferation
- dna methylation
- pi k akt