A pilot study on the use of prednisolone-encapsulated liposomes for the treatment of moderate-to-severe Graves' orbitopathy with reduced systemic steroid exposure.

Sanne E DetigerTessa M KremerVirgil A S H DalmRonald O B de KeizerRene J WubbelsJ M MetselaarP Martin van HagenRobin P PeetersDion Paridaens

Published in: Acta ophthalmologica (2021)

This pilot study showed a positive effect of long-circulating PEGylated liposomal prednisolone on the Clinical Activity Score in patients with moderate-to-severe Graves's orbitopathy, resulting in fewer hospital visits and possibly less glucocorticoid-related side-effects.

Keyphrases

high intensity
early onset
drug induced
drug delivery
healthcare
emergency department
drug release
acute care
adverse drug