Oestrogen ameliorates blood-brain barrier damage after experimental subarachnoid haemorrhage via the SHH pathway in male rats.

Jie ZhangHaiying LiZhongmou XuJinxin LuChang CaoHaitao ShenXiang LiWanchun YouHeng Gao

Published in: Stroke and vascular neurology (2022)

In conclusion, we demonstrate here that oestrogen pretreatment ameliorates brain injury after SAH, at least in part through SHH pathway-mediated BBB protection.

Keyphrases

blood brain barrier
brain injury
cerebral ischemia
subarachnoid hemorrhage
mouse model
oxidative stress