Role of Lysosomal Gene Variants in Modulating GBA-Associated Parkinson's Disease Risk.

Letizia Straniero Valeria Rimoldi Edoardo MonfriniSalvatore BonvegnaGiada Melistaccio Julie LakeGiulia SoldàMassimo Aurelinull ShankaracharyaPamela KeagleTatiana ForoudJohn E LandersCornelis BlauwendraatAnna ZecchinelliRoberto CiliaAlessio Di FonzoGianni PezzoliStefano DugaRosanna Asselta

Published in: Movement disorders : official journal of the Movement Disorder Society (2022)

The identification of genetic lesions in lysosomal genes increasing PD risk may have important implications in terms of patient stratification for future therapeutic trials. © 2022 The Authors. Movement Disorders published by Wiley Periodicals LLC on behalf of International Parkinson Movement Disorder Society.

Keyphrases

genome wide
copy number
bioinformatics analysis
case report
genome wide identification
signaling pathway
transcription factor
meta analyses