CineECG analysis provides new insights into Familial ST-segment Depression Syndrome.
Rasmus FrostedChristian Paludan-MüllerOliver Bundgaard VadMorten Salling OlesenHenning BundgaardPeter M van DamAlex Hoerby ChristensenPublished in: Europace : European pacing, arrhythmias, and cardiac electrophysiology : journal of the working groups on cardiac pacing, arrhythmias, and cardiac cellular electrophysiology of the European Society of Cardiology (2023)
CineECG analyses indicated abnormal repolarization with basal directions, and the Fam-STD ECG phenotype was simulated by reducing APD and APA in the left ventricle basal regions. Detailed ST-analysis showed amplitudes consistent with the proposed diagnostic criteria for Fam-STD patients. Our findings provide new insight into the electrophysiological abnormalities of Fam-STD.