Development of a DNA Adductome Mass Spectral Database.
Jingshu GuoRobert J TureskyAnamary TarifaAnthony P DeCaprioMarcus S CookeScott J WalmsleyPeter W VillaltaPublished in: Chemical research in toxicology (2020)
Mass spectrometry-based DNA adductomics is an emerging approach for the human biomonitoring of hazardous chemicals. A mass spectral database of DNA adducts will be created for the scientific community to investigate the associations between chemical exposures, DNA damage, and disease risk.
Keyphrases
- circulating tumor
- dna damage
- cell free
- single molecule
- mass spectrometry
- optical coherence tomography
- endothelial cells
- healthcare
- mental health
- nucleic acid
- oxidative stress
- adverse drug
- liquid chromatography
- high resolution
- circulating tumor cells
- high performance liquid chromatography
- dual energy
- magnetic resonance
- simultaneous determination
- tandem mass spectrometry