HDAC1/2 Inhibitor Romidepsin Suppresses DEN-Induced Hepatocellular Carcinogenesis in Mice.

Hara Afaloniati Katerina AngelopoulouAlexander GiakoustidisAlexandros Chardas Athanasios Pseftogas Kali Makedou Athanasios A GargavanisThomas GoulopoulosStavros IliadisVasileios PapadopoulosApostolos PapaloisGeorge MosialosTheofilos PoutahidisDimitrios Giakoustidis

Published in: OncoTargets and therapy (2020)

These findings suggest that Romidepsin, a drug currently used in the treatment of lymphoma, could also be considered in the management of early-stage HCC.

Keyphrases

early stage
drug induced
high glucose
signaling pathway
diffuse large b cell lymphoma
diabetic rats
high fat diet induced
squamous cell carcinoma
type diabetes
sentinel lymph node
metabolic syndrome
adipose tissue
endothelial cells
skeletal muscle
stress induced