Transferrin receptor 1 targeted optical imaging for identifying glioma margin in mouse models.

Xiang-Rong NiYi-Ying ZhaoHai-Ping CaiZhi-Hui YuJing WangFu-Rong ChenYan-Jiao YuGuo-Kai FengZhong-Ping Chen

Published in: Journal of neuro-oncology (2020)

The TfR 1-targeted optical probe Cy5-CRT specifically differentiates tumor tissues from the surrounding normal brain with high sensitivity, indicating its potential application for the precise surgical removal of GBM.

Keyphrases

high resolution
cancer therapy
mouse model
high speed
gene expression
resting state
white matter
quantum dots
multiple sclerosis
mass spectrometry
living cells
functional connectivity
brain injury
cerebral ischemia
fluorescence imaging
photodynamic therapy
subarachnoid hemorrhage