Immune checkpoint B7-H3 protein expression is associated with poor outcome and androgen receptor status in prostate cancer.
Caroline E Nunes-XavierWanja KildalAndreas KleppeHåvard E DanielsenHåkon WaehreRoberto LlarenaGunhild M MaelandsmoØystein FodstadRafael PulidoJose Ignacio LópezPublished in: The Prostate (2021)
These results suggest distinct clinical relevance of the two immune checkpoint proteins PD-L1 and B7-H3 in prostate cancer. Our findings highlight B7-H3 as an actionable novel immune checkpoint protein in prostate cancer.
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