NINJ2 deficiency inhibits preadipocyte differentiation and promotes insulin resistance through regulating insulin signaling.

Huixin PengYubing YuPengyun WangYufeng YaoXinna WuQian ZhengJing WangBeijia TianYifan WangTie KeMugen LiuXin TuHuiying LiuQing K WangCheng-Qi Xu

Published in: Obesity (Silver Spring, Md.) (2022)

In conclusion, these findings reveal NINJ2 as an important new facilitator of insulin receptors, and the authors propose a unique regulatory mechanism between insulin signaling, adipogenesis, and insulin resistance.

Keyphrases

type diabetes
insulin resistance
glycemic control
high fat diet induced
adipose tissue
high fat diet
metabolic syndrome
polycystic ovary syndrome
genome wide