MicroRNA-210 Downregulates TET2 (Ten-Eleven Translocation Methylcytosine Dioxygenase 2) and Contributes to Neuroinflammation in Ischemic Stroke of Adult Mice.
Yong LiRui SongGuofang ShenLei HuangDaLiao XiaoQingyi MaLubo ZhangPublished in: Stroke (2023)
miR210 inhibition reduced ischemic stroke-induced neuroinflammatory response via repression of TET2 in the adult mouse brain, suggesting that miR210 is a potential treatment target for acute brain injury after ischemic stroke.
Keyphrases
- brain injury
- cell proliferation
- long non coding rna
- atrial fibrillation
- subarachnoid hemorrhage
- cerebral ischemia
- long noncoding rna
- drug induced
- liver failure
- high glucose
- lipopolysaccharide induced
- type diabetes
- lps induced
- metabolic syndrome
- risk assessment
- insulin resistance
- oxidative stress
- aortic dissection
- adipose tissue
- blood brain barrier
- skeletal muscle
- human health
- replacement therapy