Molecular monitoring by CDKN2A/p16INK4A and RB1 gene methylation in breast cancer.
Luiz Fernando de QueirozMarcelo Soares da Mota E SilvaFernando Colonna RosmanSiane Lopes Bittencourt RosasHeitor Siffert Pereira de SouzaMaria da Gloria da Costa CarvalhoPublished in: Revista da Associacao Medica Brasileira (1992) (2024)
This study presents a novel approach for monitoring breast cancer patients through the analysis of cell-free DNA methylation. This analysis can detect changes in methylation patterns before any visible sign of cancer appears in breast tissue and could help predict the recurrence of malignant breast tumors.