Neurobrucellosis, caused by Brucella species, is a zoonotic infection that may involve the central nervous system. Although uncommon, it can manifest as a solitary intracranial mass. We report a case of neurobrucellosis in a 25-year-old woman from Peru who presented with headache, weight loss, and right-side hemiparesis and paresthesia. A contrast-enhanced magnetic resonance imaging scan revealed an intracerebral mass in the left temporal lobe. Serum testing subsequently were positive. Brain biopsy demonstrated non-necrotizing granulomas without malignant cells. Neurobrucellosis should be considered in the differential diagnosis of brain space occupying lesions in endemic countries.
Keyphrases
- contrast enhanced
- magnetic resonance imaging
- computed tomography
- diffusion weighted
- case report
- weight loss
- resting state
- induced apoptosis
- magnetic resonance
- white matter
- diffusion weighted imaging
- functional connectivity
- cell cycle arrest
- dual energy
- cerebral ischemia
- endoplasmic reticulum stress
- type diabetes
- ultrasound guided
- single cell
- cell proliferation
- signaling pathway
- cerebrospinal fluid
- oxidative stress
- brain injury
- insulin resistance
- pi k akt
- optic nerve
- blood brain barrier
- optical coherence tomography