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Primary immature teratoma of the thigh: a review.

Andreas F MavrogenisGeorge AgrogiannisKonstantinos G Toutouzas
Published in: European journal of orthopaedic surgery & traumatology : orthopedie traumatologie (2022)
Teratomas are a subtype of germ cell tumors composed of a variety of somatic tissues derived from more than one of the three germinal layers (ectoderm, endoderm and mesoderm). They can be classified as mature tumors and immature tumors. Teratomas most commonly arise at the sacrococcygeal region and the gonads. The occurrence of a teratoma outside the common gonadal and midline locations is exceptional. This review article lists the reported primary and metastatic malignant teratomas in extragonadal locations and discusses the possible explanation for the atypical location, their treatment and prognosis.
Keyphrases
  • germ cell
  • squamous cell carcinoma
  • small cell lung cancer
  • gene expression
  • copy number
  • dna methylation
  • replacement therapy