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Characterization of four virulent Klebsiella pneumoniae bacteriophages, and evaluation of their potential use in complex phage preparation.

Fedor M ZurabovEvgeniy Zhilenkov
Published in: Virology journal (2021)
The bacteriophages studied in this work are promising for further in vivo studies and might be used in phage therapy as part of a complex therapeutic and prophylactic phage preparation. The conducted studies showed that the complex preparation is more effective than individual phages. The use of the complex phage cocktail allows to extend the lytic spectrum, and significantly reduces the possibility of phage-resistant forms generation.
Keyphrases
  • pseudomonas aeruginosa
  • klebsiella pneumoniae
  • escherichia coli
  • molecularly imprinted
  • multidrug resistant
  • cystic fibrosis
  • human health
  • cell therapy