A Nationwide Hospital Claims Database Analysis of Real-World Patterns of Laxative Use for Opioid-Induced Constipation in Japanese Patients with Cancer.

Takahiro HigashibataTakaomi KessokuYasuhide MoriokaYuichi KoretakaHirokazu MishimaHidetoshi ShibaharaYuriko MasudaYasushi IchikawaAtsushi NakajimaTakayuki Hisanaga

Published in: Pain and therapy (2023)

This study demonstrated for the first time that the patterns of laxative use for OIC in Japanese patients with cancer were different, depending on the opioid types at initiation and the timing of laxative medication.

Keyphrases

chronic pain
adverse drug
pain management
healthcare
diabetic rats
high glucose
endothelial cells
oxidative stress
irritable bowel syndrome
electronic health record