Would Colloidal Gold Nanocarriers Present An Effective Diagnosis Or Treatment For Ischemic Stroke?
Hamed AmaniEbrahim MostafaviMahmoud Reza AlebouyehHamidreza ArzaghiAbolfazl AkbarzadehHamidreza Pazoki-ToroudiThomas J WebsterPublished in: International journal of nanomedicine (2019)
Collectively, our results showed that the presently formulated OX26@GNPs are not suitable nanocarriers nor contrast agents under oxidative stress for the diagnosis and treatment of ischemic stroke. Moreover, our findings suggest that the cytotoxicity of GNPs in the brain is significantly associated with their surface charge.
Keyphrases
- drug delivery
- oxidative stress
- atrial fibrillation
- cancer therapy
- drug release
- magnetic resonance
- white matter
- dna damage
- resting state
- ischemia reperfusion injury
- magnetic resonance imaging
- combination therapy
- computed tomography
- signaling pathway
- replacement therapy
- solar cells
- heat shock protein
- heat stress
- heat shock