Making a virtue out of an evil: Are red blood cells from chronic mountain sickness patients eligible for transfusions?

Emeric StaufferAurélien P PichonBenoit ChampigneulleMichaël FurianIvan HanccoAlexis DarrasPaul RobachJulien V BrugniauxElie NaderPhilippe ConnesSamuel Verges Lars Kaestner

Published in: American journal of hematology (2024)

We investigated highlanders, permanently living at an altitude of 5100 m and compared Chronic Mountain Sickness (CMS) patients with control volunteers. While we found differences in systemic parameters such as blood oxygen content, hematocrit, hemoglobin concentration, and blood viscosity, the mechanical and rheological properties of single red blood cells did not differ between the two investigated groups.

Keyphrases

red blood cell
end stage renal disease
newly diagnosed
ejection fraction
chronic kidney disease
atomic force microscopy
peritoneal dialysis
prognostic factors
high resolution
patient reported